Glycyrrhizic Acid as a Novel Drug Delivery Vector: Synergy of Drug Transport and Efficacy
نویسندگان
چکیده
منابع مشابه
Glycyrrhizic Acid as a Novel Drug Delivery Vector: Synergy of Drug Transport and Efficacy
Supramolecular drug delivery systems (DDS) are widely used in pharmacology during last decades for designing new preparations with improved properties. Most of fundamental and applied research in this field has been devoted to the inclusion complexes with cyclodextrins (CD), which are assumed to possess protective properties and to decrease the hydrophobic behavior of the included molecules. At...
متن کاملPreparation and evaluation of vitamin A nanosuspension as a novel ocular drug delivery
Objective(s): The aim of this study was to prepare a nanosuspension formulation as a new vehicle for the improvement of the ocular delivery of vitamin A. Material and Methods: Formulations were designed based on full factorial design. A high pressure homogenization technique was used to produce nanosuspensions. Fifteen formulations were prepared by the use of different combinations of surfa...
متن کاملBioavailability enhancement of paclitaxel via a novel oral drug delivery system: paclitaxel-loaded glycyrrhizic acid micelles.
Paclitaxel (PTX, taxol), a classical antitumor drug against a wide range of tumors, shows poor oral bioavailability. In order to improve the oral bioavailability of PTX, glycyrrhizic acid (GA) was used as the carrier in this study. This was the first report on the preparation, characterization and the pharmacokinetic study in rats of PTX-loaded GA micelles The PTX-loaded micelles, prepared with...
متن کاملNovel transdermal drug delivery systems
Background and aim: Eczema is a common inflammatory skin disease. Although history and physical examination are important in diagnosis of allergen, because of extent of environmental allergens, those are not simply recognized. The objective of this study was to determine allergens in patients with contact or atopic dermatitis referred to Razi hospital.Materials and Meth...
متن کاملAdenovirus Dodecahedron, as a Drug Delivery Vector
BACKGROUND Bleomycin (BLM) is an anticancer antibiotic used in many cancer regimens. Its utility is limited by systemic toxicity and dose-dependent pneumonitis able to progress to lung fibrosis. The latter can affect up to nearly 50% of the total patient population, out of which 3% will die. We propose to improve BLM delivery by tethering it to an efficient delivery vector. Adenovirus (Ad) dode...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Open Conference Proceedings Journal
سال: 2011
ISSN: 2210-2892
DOI: 10.2174/2210289201102010064